Immunology Group (MIG) Request for Proposals (RFP)
The purpose of this funding opportunity is to
support innovative research projects from basic,
applied, or translational scientists and
clinicians working in HIV mucosal immunity in
order to advance one or more of the MIG
scientific areas of interest. Proposed research
activities should be consistent with current
NIH HIV/AIDS research priorities.
Proposals responding to the MIG RFP should
address one or more of the following four
scientific areas of interest:
1. Develop improved methodologies to interrogate and analyze the tissue microenvironment, mucosal fluids, and cellular and molecular interactions within human genital, oral, lung, and colorectal mucosa as these factors relate to HIV infection and/or immune responses to HIV.
2. Develop and advance human mucosal tissue models that may more closely mimic HIV interactions in an intact mucosal environment and provide potentially more predictive value to better inform product decisions for multiple HIV preventive and therapeutic modalities.
3. Evaluate the role of gut, oral, lung and genital microbiomes (bacteria, fungi, viruses) in modulating the effects of HIV prevention and therapeutic interventions, particularly vaccine-mediated responses, in mucosal tissues and fluids.
4. Explore the dynamics of mucosal HIV-1 latent
reservoir formation in breakthrough
cases/controls within HIV vaccine,
immunoprophylaxis, and immunotherapeutic
studies, with a goal to gain insight into the
contribution of pre- and post-infection immune
responses on the reservoir size and kinetics.
September 4, 2018, investigators
interested in applying for a MIG award should
have completed the following:
Download the complete MIG Aug 1, 2018 RFP
Download the MIG Checklist for inclusion in your
• Complete your application including all necessary budget,
project scope, personnel and supporting information requested in the full MIG
RFP announcement application
• A signed Letter of Intent on your institutional letterhead;
a separate LOI is required for each PI or co-PI on the application in order for
a sub-award to be issued.
(Download LOI example template here)
Securely upload your complete application file
as a PDF (please limit file size to ~10MB or less) using the appropriate
naming convention. You will receive a confirmatory e-mail once your application
has been successfully uploaded.
MIG awards will be for one year with maximum funding per application of up to $90,000 Total Costs.
Because of accelerated funding timelines, if awarded, successful applicants will be expected to begin work immediately upon receipt of funds.